Measure promoter activity in living cells in a high-throughput, efficient, and economic way.
- SwitchGear's genome-wide set of promoters are defined by the only experimentally-trained prediction algorithm
- Spend time conducting experiments rather than creating reagents and resources by taking advantage of SwitchGear's optimized reporter system and sequence-verified clones
- Use the Promoter Macroarray to measure promoter activity across diverse cell types or through different experimental time-courses
- Use the Promoter Macroarray to broaden the scope of a research project or deepen the biological study of a particular pathway
- Utilize Switchgear's Promoter Family Sets to focus on specific regulatory networks such as apoptosis, hypoxia, or DNA-damage (see SwitchDB for more details).
- Take advantage of SwitchGear's data analysis tools and informatics resources
SwitchGear's Promoter MacroArrays measure the activity of thousands of unique human promoters in a single experiment.
Measuring promoter activity characterizes:
- The mechansim by which a gene is induced or repressed
- The functional consequences of transcription factor binding
- The effect of sequence variants on promoter function
CLICK HERE FOR FUNCTIONAL PROMOTER MACROCARRAY PRODUCT DETAILS
Gene Family and Pathway Subsets (for detailed information, go to SwitchDB):
- Promoter Control Plate (8 contructs)
- Hypoxia (~400 promoters)
- Nuclear Receptors (~1,200 promoters)
- Total Oncology (~3,000 promoters)
- DNA-damage (~500 promoters)
- Apoptosis (~1,000 promoters)
- Cell Cycle (~1,000 promoters)
- p53 (~100 promoters)
- Total Chr7 (~2,000)